
Radioactive iodine (RAI) therapy is a safe and effective treatment for hyperthyroidism and certain types of thyroid cancer. The treatment involves the use of radioactive iodine-131 (I-131) isotopes, which are absorbed by the thyroid gland and destroy the thyroid gland and any other thyroid cells, including cancer cells. The treatment is typically administered as a pill, liquid, or injection in a hospital or outpatient clinic. While the procedure itself is brief, patients may need to stay in the hospital for a few days after treatment to prevent radiation exposure to others. During this time, patients may experience side effects such as dry mouth, altered sense of taste, and inflamed salivary glands.
| Characteristics | Values |
|---|---|
| Treatment type | Radioactive iodine therapy (RAI) |
| Treatment for | Hyperthyroidism and thyroid cancer |
| Treatment procedure | Oral or IV injection |
| Hospitalization | May vary depending on the dose and other factors |
| Treatment duration | Brief |
| Post-treatment precautions | Avoid pregnant women and children, stay a certain distance from others, use separate utensils, etc. |
| Side effects | Dry mouth, altered sense of taste, inflamed salivary glands, etc. |
| Post-treatment diet | Drink plenty of fluids, suck on gum or candy |
| Radiation exposure | Low levels of radiation for some time after treatment |
| Pregnancy | Not safe during pregnancy, avoid getting pregnant for at least 6 months after treatment |
| Breastfeeding | Need to stop at least 6 weeks before the procedure |
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What You'll Learn
- Radioactive iodine therapy is used to treat thyroid cancer and hyperthyroidism
- The treatment can be administered via injection or by mouth
- Patients may need to be hospitalised for a few days after treatment
- It can cause short-term side effects like dry mouth and inflamed salivary glands
- Patients should avoid pregnant women and children after treatment

Radioactive iodine therapy is used to treat thyroid cancer and hyperthyroidism
Radioactive iodine therapy is a safe and effective treatment for hyperthyroidism and certain types of thyroid cancer. It is also known as radioisotope therapy, radionuclide therapy, or RAI (radioactive iodine ablation or radioiodine ablation). The treatment is administered in a hospital, either as a tablet or capsule (sometimes a liquid), or through an IV injection. The patient may be required to stay in the hospital for a few days after the treatment.
Radioactive iodine therapy is used to treat thyroid cancer by destroying thyroid cancer cells. It is suitable for some types of thyroid cancer, including follicular and papillary thyroid cancer, and can be used even if the cancer has spread to other parts of the body. RAI is usually recommended for papillary, follicular, or oncocytic thyroid cancers that have spread to the lymph nodes or have a high risk of recurrence after surgery. It is not typically given for smaller cancers that have not spread and is ineffective for medullary or anaplastic thyroid cancers.
Before the treatment, the patient may need to follow a low-iodine diet for one to two weeks to prepare the thyroid cells to absorb the radioactive iodine. This involves limiting or avoiding foods such as iodized salt, red dye #3, dairy products, eggs, seafood, and soy. In addition, the patient may need to stop breastfeeding at least six weeks before the procedure and take a pregnancy test, as RAI therapy is not safe during pregnancy.
Radioactive iodine therapy is also used to treat hyperthyroidism, a condition where the thyroid gland produces an excessive amount of thyroid hormone. The treatment destroys most or all of the tissue in the thyroid gland, reducing hormone production. Doctors often use RAI if hyperthyroidism recurs after treatment with antithyroid medicine or surgery. It offers the best chance of permanently curing hyperthyroidism, and most people only need one dose. However, it can cause side effects such as a metallic taste in the mouth, sore throat, neck pain, nausea, and vomiting.
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The treatment can be administered via injection or by mouth
Radioactive iodine (RAI) therapy is used to treat hyperthyroidism and certain types of thyroid cancer. It is a safe and effective treatment that targets and kills thyroid cells. The treatment can be administered via injection or by mouth, and most people only need one dose.
If you are getting RAI therapy for thyroid cancer, you will be given a larger dose than if you are treating hyperthyroidism. The dose is administered either by taking a pill, drinking a liquid, or getting an injection into your vein. The procedure is typically brief, but the preparation and post-procedure precautions are more time-intensive.
Before receiving RAI therapy, you will need to follow a low-iodine diet for 1-2 weeks. This involves limiting or avoiding foods that contain iodized salt, red dye #3, dairy products, eggs, seafood, and soy. You may also need to stop breastfeeding and take injections of thyroid-stimulating hormone (TSH) to increase the amount of radioactive iodine your thyroid will absorb.
After the procedure, you may experience side effects such as neck tenderness and swelling, salivary gland swelling, inflammation in the stomach lining (gastritis), taste changes, dry mouth, and fatigue. To reduce the risk of dry mouth, it is recommended to drink plenty of fluids during your hospital stay and chew gum or suck on hard candy. Most of the radioactive iodine will leave your body through your urine in the first few days after treatment.
In conclusion, RAI therapy is a safe and effective treatment for hyperthyroidism and certain types of thyroid cancer. The treatment can be administered via injection or by mouth, and most people only need one dose. It is important to follow the recommended diet and precautions before and after the procedure to ensure a successful treatment outcome.
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Patients may need to be hospitalised for a few days after treatment
Radioactive iodine (RAI) therapy is a safe and effective treatment for hyperthyroidism and certain thyroid cancers. It has been used to treat thyroid cancer for about 80 years. During treatment, a patient swallows a prepared dose of RAI, or it is injected intravenously. The iodine is absorbed into the bloodstream and collected by the thyroid gland, where it destroys the thyroid's cells.
Due to the nature of the treatment, patients may need to be hospitalised for a few days after receiving RAI therapy. This is because the body gives off low levels of radiation following RAI therapy, and patients may need to stay in a special isolation room to prevent others from being exposed to radiation. The length of the hospital stay depends on the dose given and where the treatment was received.
After treatment, patients will be advised to drink plenty of fluids, and doctors may recommend chewing gum or sucking on sweets to keep the salivary glands working. This is because RAI treatment can cause salivary glands to become inflamed, leading to symptoms such as swelling, pain, and a dry mouth.
Patients will also be advised to avoid close contact with other people, especially pregnant women and children, for several days after treatment. This is due to the risk of radiation exposure to those around the patient. Patients with infants at home should arrange for alternative care for their children for a few days after treatment.
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It can cause short-term side effects like dry mouth and inflamed salivary glands
Radioactive iodine (RAI) therapy is a safe and effective treatment for hyperthyroidism and certain types of thyroid cancer. It involves administering a dose of radioactive iodine into the body by mouth or through an IV injection. The iodine is absorbed by the thyroid gland, and the radiation emitted destroys the gland and any other thyroid cells, including cancer cells.
While RAI therapy is typically a brief procedure, it can cause several short-term side effects, including dry mouth and inflamed salivary glands. The salivary glands can become inflamed after RAI treatment, leading to symptoms such as swelling and pain. This inflammation can result in reduced saliva production, causing a dry mouth. These side effects usually resolve with time, but they may persist in a small number of people.
To manage dry mouth and salivary gland inflammation, it is recommended to drink plenty of fluids during and after the hospital stay. Chewing gum or sucking on hard candy can also help stimulate the salivary glands and alleviate dry mouth. In cases of severe inflammation and pain, doctors may prescribe painkillers or medication to reduce inflammation.
In addition to dry mouth, RAI therapy may cause other short-term side effects, such as altered taste and smell, fatigue, nausea, and inflammation of the tummy or bladder (gastritis). These side effects generally subside within weeks to a year after treatment.
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Patients should avoid pregnant women and children after treatment
Radioactive iodine treatment is a safe and effective treatment for hyperthyroidism and certain types of thyroid cancer. The treatment involves the administration of a dose of radioactive iodine, which collects mainly in thyroid cells and destroys the thyroid gland and any other thyroid cells, including cancer cells. The radiation from this treatment has less of an effect on the rest of the body. However, it is important to take certain precautions to protect others around you, as you will emit radiation through bodily fluids like urine, saliva, and sweat for a few days after the procedure.
One of the key precautions advised by healthcare professionals is to avoid close and prolonged contact with others, especially pregnant women and children, for a couple of weeks. This precaution is crucial because exposure to radiation is particularly risky for pregnant women and children. Radioactive iodine can pass through the placenta and negatively affect fetal development, increasing the risk of abortion, premature birth, and birth defects. Therefore, women are generally advised to wait for at least six months after radioactive iodine treatment before trying to conceive.
To minimize contact, patients may need to sleep in a separate bed, avoid hugging and kissing, and use their own towels, cutlery, and plates until washed. They should also practice good hygiene, such as flushing the toilet twice and washing their hands thoroughly afterward. Additionally, patients should be aware that they may set off radiation alarms at airports due to the recent treatment, so it is advisable to carry a certificate or letter from their doctor when travelling.
It is important to note that these precautions are temporary, and the healthcare team will advise on the specific duration and any additional measures to ensure the safety of both the patient and those around them. The side effects of the treatment, such as salivary gland inflammation and dry mouth, can be managed with medication and by drinking plenty of fluids. Overall, the treatment is generally well-tolerated, and the benefits of effectively treating hyperthyroidism and thyroid cancer outweigh the risks associated with radiation exposure.
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Frequently asked questions
Radioactive iodine treatment is typically an outpatient procedure, meaning you will not need to stay in the hospital overnight. However, depending on the size of the dose and other factors, your doctor may recommend staying in the hospital for a few days after the treatment to ensure your safety and prevent radiation exposure to others.
Radioactive iodine is eliminated from the body within a few days, primarily through urination. Small amounts may also be excreted through saliva, sweat, tears, vaginal secretions, and feces.
Yes, there are several side effects and precautions to consider after radioactive iodine treatment. You may experience inflammation of the salivary glands, resulting in symptoms such as dry mouth, swelling, and pain. It is recommended to drink plenty of fluids and chew gum or suck on candy to alleviate these symptoms. Additionally, the treatment can cause gastrointestinal issues, such as inflammation of the stomach lining (gastritis).
Yes, but there are some considerations to keep in mind. Recent radioactive iodine treatment may set off radiation alarms at airports, so it is advisable to carry a certificate or letter from your doctor explaining your treatment. Additionally, if your work or daily activities involve prolonged contact with small children or pregnant women, it is recommended to wait several days before resuming these activities to minimize radiation exposure to others.
Yes, it is recommended to avoid pregnancy and conception for at least six months to one year after the treatment. Radioactive iodine may affect fertility in both men and women, so it is important to discuss family planning and fertility preservation options with your doctor before starting treatment.











































