
The NIH Clinical Center, also known as Building 10, is a hospital dedicated to clinical research at the National Institutes of Health campus in Bethesda, Maryland. The Clinical Center consists of the original hospital, the Warren Grant Magnuson Clinical Center, and the newest addition, the Mark O. Hatfield Clinical Research Center. The NIH Clinical Center integrates patient care with clinical trials, with patients participating in research studies and receiving treatment without charge.
| Characteristics | Values |
|---|---|
| Name | National Institutes of Health Clinical Center |
| Location | Bethesda, Maryland, USA |
| Area | 250,000 ft² |
| Number of Buildings | 75+ |
| Year of Construction | 1948-1953 |
| Year of Renovation | 2017 |
| Renovation Cost | $322 million |
| Number of Floors | 16 |
| Number of Inpatient Beds | 200 |
| Number of Operating Rooms | 11 |
| Number of Day Hospital Stations | 93 |
| Number of Research Protocols in 2014 | 1,611 |
| Percentage of Clinical Trials in 2014 | 48% |
| Percentage of Natural History Studies in 2014 | 46% |
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What You'll Learn

The NIH Clinical Center is a hospital dedicated to clinical research
The NIH Clinical Center, also known as Building 10, is a hospital dedicated solely to clinical research. Located on the NIH campus in Bethesda, Maryland, the hospital has been operational since 1953. It consists of two parts: the original Warren Grant Magnuson Clinical Center and the newer Mark O. Hatfield Clinical Research Center, which are connected to form one large building.
The Clinical Center provides a unique environment for patient care and the conduct of clinical trials, with approximately 1,600 clinical research studies in progress. About half of these studies focus on the natural pathogenesis of rare diseases, which are often understudied elsewhere. The other half includes clinical trials, natural history studies, and screening and training protocols. The center is equipped with 200 inpatient beds, 11 operating rooms, 93 day hospital stations, critical care services, research labs, and a range of imaging services.
The NIH Clinical Center is known for its state-of-the-art infrastructure, including isolation capabilities and infection control measures, which are essential for patient safety during clinical research studies. Since its opening, more than 500,000 research volunteers have participated in studies at the Clinical Center, contributing to numerous medical breakthroughs. These include the first successful cure of cancerous solid tumors with chemotherapy, the use of nitroglycerin to treat heart attacks, the identification of a genetic component in schizophrenia, and the development of blood tests for Acquired Immune Deficiency Syndrome (AIDS) and hepatitis.
The center's clinician-investigators play a crucial role in translating scientific observations and laboratory discoveries into new approaches for diagnosing, treating, and preventing diseases. Their work has been recognized with awards such as the 2011 Lasker~Bloomberg Public Service Award, acknowledging the center's role as a model research hospital. The NIH Clinical Center actively collaborates with other institutions and seeks to train and mentor the next generation of clinical researchers.
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It is located in Bethesda, Maryland, USA
The National Institutes of Health (NIH) Clinical Center, also known as Building 10, is located in Bethesda, Maryland, USA. The NIH Clinical Center is a hospital solely dedicated to clinical research. It is part of the NIH campus, which is situated just 10 miles from the center of Washington, DC.
The Clinical Center consists of two parts: the original hospital, the Warren Grant Magnuson Clinical Center, and the newest addition, the Mark O. Hatfield Clinical Research Center. These two parts are connected to form one large building. The hospital has 200 inpatient beds, 11 operating rooms, 93 day hospital stations, critical care services, research labs, an ambulatory care research facility, and advanced imaging services.
The NIH Clinical Center is unique in that it is one of the few facilities in the world with state-of-the-art infrastructure that allows for isolation capabilities and infection control during clinical research studies. Patients at the Clinical Center participate in research studies, also known as protocols, and receive treatment without charge. However, admission is selective. Patients must have a medical condition under study by NIH Institutes or Centers and meet specific inclusion criteria to enroll in the studies.
Since its opening in 1953, NIH scientists have worked with volunteer patients to create groundbreaking medical innovations. Notable successes include pioneering the cure of cancerous solid tumors with chemotherapy, identifying a genetic component in schizophrenia, and developing blood tests to identify Acquired Immune Deficiency Syndrome (AIDS) and hepatitis.
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The hospital has 200 inpatient beds and 11 operating rooms
The NIH Clinical Center, also known as Building 10, is a hospital dedicated to clinical research at the National Institutes of Health campus in Bethesda, Maryland. The hospital has 200 inpatient beds and 11 operating rooms, along with 93 day hospital stations, critical care services, and research labs. The Clinical Center provides an environment for patient care and conducting clinical trials, with most trials being in Phase I or Phase II. The hospital has been at the forefront of medical innovations since its opening in 1953, with NIH scientists working closely with volunteer patients.
One of the unique aspects of the Clinical Center is its specialized hospital design, which places patient care units in close proximity to research laboratories. This model fosters interaction and collaboration among clinical researchers, contributing to its dynamic environment. The hospital's infrastructure enables isolation capabilities and infection control, making it one of the few facilities globally with such advanced features.
The NIH Clinical Center has a selective admission process. Patients must have a medical condition under study by the NIH Institutes or Centers and meet specific inclusion criteria to enroll in the research studies. In 2014, there were 1,611 active research protocols at the Clinical Center, with a focus on various areas such as cancer, infectious diseases, blood disorders, heart disease, and lung disease. The center integrates data from intramural clinical trials into a repository called the Biomedical Translational Research Information System (BTRIS).
The hospital is renowned for its significant contributions to medical advancements. Some of its notable successes include pioneering the cure for cancerous solid tumors with chemotherapy, using nitroglycerin to treat heart attacks, identifying a genetic component in schizophrenia, and conducting the first successful replacement of a mitral valve for heart disease treatment. The Clinical Center has also developed blood tests to identify Acquired Immune Deficiency Syndrome (AIDS) and hepatitis.
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It has a multi-year, $322 million renovation project ongoing
The NIH Clinical Center, also known as Building 10, is a hospital dedicated solely to clinical research at the National Institutes of Health campus in Bethesda, Maryland. The hospital has been undergoing a multi-year, $322 million renovation project to upgrade its facilities and infrastructure. This renovation project aims to enhance the Clinical Center's capabilities in conducting clinical research and providing patient care.
The NIH Clinical Center has a long history of medical innovations since its opening in 1953. The hospital has been at the forefront of medical advancements, including the cure of cancerous solid tumors with chemotherapy, the use of nitroglycerin to treat heart attacks, and the identification of a genetic component in schizophrenia. The Clinical Center is also known for its success in conducting the first replacement of a mitral valve to treat heart disease and the creation of blood tests to identify Acquired Immune Deficiency Syndrome (AIDS) and hepatitis.
The renovation project aims to further enhance the Clinical Center's capabilities and maintain its position as a leader in clinical research. The project involves upgrading the hospital's infrastructure, including its inpatient beds, operating rooms, day hospital stations, critical care services, research labs, and imaging services. The renovations will also improve the hospital's ability to conduct isolation capabilities and infection control during clinical research studies.
The NIH Clinical Center is unique in its ability to integrate patient care and cutting-edge clinical trials. In 2014, the hospital had 1,611 active research protocols, with a focus on clinical trials, natural history studies, and screening and training protocols. The renovation project will ensure that the Clinical Center can continue to conduct innovative research and provide the highest level of patient care.
The multi-year renovation project is a significant investment in the future of the NIH Clinical Center and its mission to advance medical knowledge and patient care. The project reflects the hospital's commitment to staying at the forefront of clinical research and adapting to the evolving needs of patients and the medical community. With its state-of-the-art infrastructure and dedicated team of researchers and medical professionals, the NIH Clinical Center is well-positioned to continue its legacy of medical innovations.
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The NIH Clinical Center is a teaching hospital
The NIH Clinical Center, located in Bethesda, Maryland, is a teaching hospital. It is the nation's largest hospital devoted entirely to clinical research. The Clinical Center is officially known as Building 10 and consists of the original part of the hospital, the Warren Grant Magnuson Clinical Center, and the newest addition, the Mark O. Hatfield Clinical Research Center. These two parts are connected to form one large building.
Since its opening in 1953, the NIH Clinical Center has focused on understanding, diagnosing, and treating illnesses, working in partnership with patients. The center sees two types of research participants: patient volunteers and healthy volunteers. Patient volunteers are people with specific diseases or conditions who help medical investigators learn more about their condition or test new medications, procedures, or treatments. Healthy volunteers, on the other hand, have no known significant health problems and play a crucial role in testing new drugs, devices, or interventions. Each year, about 10,000 new research participants join the center, contributing to the advancement of medical knowledge.
The NIH Clinical Center provides an environment for both patient care and conducting clinical trials, with a particular focus on rare and severe diseases. About 1,600 clinical research studies are in progress at the center, with approximately half dedicated to understanding the natural history of diseases, especially rare ones. This focus on rare diseases adds to the understanding of more common diseases as well. The clinical trials at the NIH Clinical Center are predominantly Phase I and Phase II, often involving first-in-human tests to evaluate safety and efficacy.
The center is equipped with state-of-the-art infrastructure, including 200 inpatient beds, 11 operating rooms, 93 day hospital stations, critical care services, research labs, and advanced imaging services. It is one of the few facilities in the world capable of providing isolation capabilities and infection control during clinical research studies. The NIH Clinical Center's collaborative environment encourages clinician-scientists to pursue innovative ideas, leading to numerous medical breakthroughs over the years.
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Frequently asked questions
Yes, the NIH Clinical Centre is in Building 10 on the National Institutes of Health campus in Bethesda, Maryland.
The NIH Clinical Centre is a hospital solely dedicated to clinical research. It is also a teaching hospital.
Construction of the Clinical Centre began in 1948 and it opened in 1953.
The Clinical Centre provides an environment for both patient care and conducting clinical trials. Patients consent to participate in research studies and are treated without charge.











































