
Primary peritoneal cancer is a rare form of cancer that affects the thin layer of cells lining the inside wall of the abdomen, known as the peritoneum. It can be difficult to treat and often requires advanced treatments such as cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC). When choosing a hospital for primary peritoneal cancer treatment, it is important to consider the expertise of the medical team and the availability of specialized treatments and clinical trials. Some top hospitals in the United States for treating primary peritoneal cancer include the Cleveland Clinic, Fox Chase Cancer Center in Philadelphia, PA, UT Southwestern Medical Center in Dallas, Texas, UC San Diego Health, and Mount Sinai in New York. These centers offer comprehensive care, access to clinical trials, and specialized treatments for primary peritoneal cancer.
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What You'll Learn
- The Cleveland Clinic offers personalized treatment for primary peritoneal cancer
- The Harold C. Simmons Comprehensive Cancer Center provides advanced treatments for peritoneal cancer
- Fox Chase Cancer Center offers personalized treatment options for primary peritoneal cancer
- UC San Diego Health provides expert peritoneal cancer care and is ranked among the top 50 in the US
- Mount Sinai, New York, is at the forefront of treating peritoneal malignancies

The Cleveland Clinic offers personalized treatment for primary peritoneal cancer
Primary peritoneal cancer is a rare cancer of the peritoneum, a thin layer of tissue lining the abdomen. It occurs when the epithelial cells in the peritoneum grow abnormally. The peritoneum covers many organs inside the abdomen, including the bladder, intestines, rectum, and uterus.
The Cleveland Clinic offers expert diagnosis and personalized treatment for primary peritoneal cancer. Recognized in the U.S. and worldwide for its expertise and care, Cleveland Clinic is a trusted healthcare leader. As a National Cancer Institute (NCI)-designated comprehensive cancer center, Cleveland Clinic consistently meets and exceeds high standards for cancer research, diagnosis, and treatment.
Cleveland Clinic's team-based approach ensures that patients receive the support and expertise of all the healthcare providers they need in one place. The clinic's specialists are experienced in treating rare cancers and understand the impact of a rare cancer diagnosis on patients' lives. They provide compassionate care and guidance throughout the treatment journey, making sure patients have the best care, support, and resources they need.
Cleveland Clinic offers personalized treatment for primary peritoneal cancer, including surgery, systemic therapy, and HIPEC (hyperthermic intraperitoneal chemotherapy). Clinical trials are also underway to discover additional treatment options and improve outcomes. Patients can easily access Cleveland Clinic's peritoneal cancer experts and receive financial assistance and billing information.
With locations in Northeast Ohio, Akron General, Union Hospital, Florida, and London, Cleveland Clinic provides convenient access to expert care. The clinic also offers virtual visits for patients who cannot easily travel to their providers' offices, ensuring they receive the same high-quality care from the comfort of their homes.
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The Harold C. Simmons Comprehensive Cancer Center provides advanced treatments for peritoneal cancer
The Harold C. Simmons Comprehensive Cancer Center is a leader in cancer research and treatment, offering advanced treatments for peritoneal cancer. As the only National Cancer Institute (NCI)-designated comprehensive cancer center in North Texas, the facility provides patients with access to the latest treatments and clinical trials.
Peritoneal cancer is a rare form of cancer that develops in the peritoneum, the thin membrane lining the abdomen and covering organs like the bladder, intestines, and uterus. It can be primary peritoneal cancer, originating in the peritoneum, or secondary peritoneal cancer, which spreads to the peritoneum from elsewhere in the body.
The Harold C. Simmons Comprehensive Cancer Center, located in Dallas, Texas, specializes in treating this rare form of cancer. Their multidisciplinary team offers advanced treatments, including cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC). This complex treatment approach is only available at select top cancer centers and is tailored to patients with primary and secondary peritoneal cancer.
The center's Peritoneal Malignancies and HIPEC Program provides expert diagnosis, staging, and treatment planning for peritoneal cancer. Their cancer specialists have extensive experience in evaluating and treating peritoneal cancer, ensuring accurate diagnoses and effective treatment plans. The center also offers support services, such as cancer nutrition and rehabilitation, to improve patients' quality of life during treatment.
In addition to advanced treatments, the Harold C. Simmons Comprehensive Cancer Center provides access to clinical trials for emerging therapies. As an NCI-designated center, they offer a broad range of clinical trials, giving patients access to potential therapies not widely available. This aspect enables patients to contribute to cancer research while benefiting from the latest advancements.
The center is committed to providing the highest level of cancer care and has received recognition for its excellence. With a dedicated team of leading cancer physicians and oncology-trained support staff, the center strives to return patients with cancer to good health through innovative treatments and compassionate care.
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Fox Chase Cancer Center offers personalized treatment options for primary peritoneal cancer
Primary peritoneal cancer is a rare form of cancer that develops in the peritoneum, a thin membrane lining the abdomen and covering several organs, including the bladder, intestines, rectum, and uterus. It is often confused with ovarian cancer due to their similar symptoms and the possibility of ovarian cancer spreading to the peritoneum.
Fox Chase Cancer Center in Philadelphia, PA, is a leading cancer care institution that offers comprehensive treatment options for primary peritoneal cancer. The centre's multidisciplinary medical team, led by gynecologic oncologist Dr. Stephanie King, provides personalized treatment plans tailored to each patient's unique needs.
The treatment approach at Fox Chase Cancer Center focuses on controlling the cancer, preserving function, and reducing the risk of recurrence. The centre's experienced medical professionals work closely with patients to understand their specific circumstances and determine the most suitable treatment options. This collaborative process involves regular reviews of patient cases and in-depth discussions to reach a consensus on treatment strategies.
Fox Chase Cancer Center offers a range of treatment options, including innovative surgical techniques, combination therapies, and systemic therapies such as targeted therapy, immunotherapy, and chemotherapy. The centre also provides access to clinical trials for emerging and innovative therapies, allowing patients to benefit from the latest advancements in cancer treatment.
The centre's medical oncologists are regional and national leaders in treating primary peritoneal cancer, ensuring that patients receive the highest quality care. Fox Chase Cancer Center is committed to providing personalized care, utilizing its vast network of leading physicians and cutting-edge clinical trials to offer the best possible treatment outcomes for its patients.
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UC San Diego Health provides expert peritoneal cancer care and is ranked among the top 50 in the US
UC San Diego Health is ranked among the top 50 in the US for cancer care by US News and World Report. Moores Cancer Center at UC San Diego Health is the only National Cancer Institute (NCI)-designated Comprehensive Cancer Center in San Diego County. This is the highest possible rating for a US cancer centre, meaning patients receive the best possible care and support. Moores Cancer Center is also recognised as one of the nation's top cancer centres for many years, including 2024 and 2025-26, when it was ranked 41st.
UC San Diego Health provides expert peritoneal cancer care. Peritoneal cancer is a rare cancer that spreads to the peritoneum, the thin layer of cells that line the inside wall of the abdomen and cover the uterus, bladder, stomach, intestines and rectum. Cancer that originates in the peritoneum is called primary peritoneal cancer. UC San Diego Health's surgical oncology team is internationally recognised for its expertise in treating this rare but serious type of abdominal cancer. The centre's specialists care for more patients with peritoneal and other gastrointestinal cancers than any other San Diego healthcare system.
The first-line treatment for peritoneal cancer is surgery to remove tumours, followed by heated intraperitoneal chemoperfusion (HIPEC). UC San Diego Health is one of the most experienced medical centres in the world at this procedure, performing more HIPEC procedures than any other medical centre in the western United States, with high success rates. The centre's cancer specialists work out of the same building, making it easier to compare notes, discuss patient treatment options, and review patient progress.
UC San Diego Health also offers a same-day cancer care clinic that provides fast, expert treatment for urgent cancer-related symptoms, improving patient care and quality of life. The centre provides the highest level of care and the most advanced treatment options in a warm and supportive environment. UC San Diego Health's oncologists provide personalised care with better outcomes and set treatment standards nationwide for more than 200 types of cancer.
Other top cancer centres for peritoneal cancer treatment include the Cleveland Clinic, which provides expert and compassionate care, and the Fox Chase Cancer Center in Philadelphia, which offers personalised treatment options for ovarian and primary peritoneal cancer patients. The Harold C. Simmons Comprehensive Cancer Center at UT Southwestern Medical Center in Texas is also a top centre, offering the most advanced treatments, including cytoreductive surgery and HIPEC.
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Mount Sinai, New York, is at the forefront of treating peritoneal malignancies
The Mount Sinai Health System in New York City has been at the forefront of treating peritoneal malignancies. Dr Daniel Labow, a leading peritoneal mesothelioma surgeon, was previously associated with Mount Sinai for nearly 20 years. He founded and directed the hospital's HIPEC program, performing hundreds of life-saving chemotherapy procedures. HIPEC is an advanced treatment that combines cytoreductive surgery with heated chemotherapy to remove tumours from the abdominal lining.
Mount Sinai's Brooklyn Heights facility offers comprehensive consultations and personalised treatment plans for various cancers, including peritoneal malignancies. They provide advanced surgical procedures and exclusive treatment options like hyperthermic intraperitoneal chemotherapy (HIPEC) for tumours in the abdominal (peritoneal) lining. This treatment is used for tumours stemming from colon, gastric, ovarian, and appendiceal cancers, as well as mesothelioma.
The hospital's commitment to cancer treatment is evident through initiatives like the Surgical Oncology Fellowship, supervised clinical trials, and the publication of dozens of medical articles. Mount Sinai's efforts in cancer research and education have contributed to improving patient experiences and advancing the field of oncology. Their work in peritoneal cancer treatment exemplifies their dedication to tackling rare and challenging malignancies.
In addition to Mount Sinai, other medical centres are also contributing to advancements in treating peritoneal cancer. The Cleveland Clinic, for instance, offers expert and compassionate care, providing personalised treatment plans and support throughout diagnosis, treatment, and beyond. The Fox Chase Cancer Center in Philadelphia, PA, provides personalised treatment options for ovarian and primary peritoneal cancer, utilising the experience of their multidisciplinary medical team. These centres, along with Mount Sinai, are actively involved in improving treatment options and patient care for individuals facing peritoneal malignancies.
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