
Vaccination has been a key tool in the fight against COVID-19, with studies showing that vaccines are highly effective in reducing hospitalizations, severe illnesses, and deaths. However, there have been concerns about the percentage of vaccinated individuals who still end up hospitalized with COVID-19. While the majority of hospitalized patients during the pandemic have been unvaccinated, there have been reports of vaccinated individuals requiring hospitalization as well. The percentage of vaccinated individuals among hospitalized COVID-19 patients has varied across different regions and time periods. For example, in Alabama, around 32% of hospitalized patients had been vaccinated during a record surge in January 2022. In contrast, other sources have reported lower percentages, such as less than 1% in Minnesota and 2% in Ohio. Overall, studies suggest that vaccinated individuals who are hospitalized with COVID-19 tend to have milder symptoms, and the risk of hospitalization is significantly lower for vaccinated individuals compared to the unvaccinated population.
| Characteristics | Values |
|---|---|
| Percentage of hospitalized patients vaccinated in Alabama | 32% |
| Percentage of Alabamans fully vaccinated | Less than 48% |
| Percentage of COVID-19 hospitalizations among 18-29-year-olds in New Jersey | Increased by 58% since the beginning of the year |
| Percentage of COVID-19 hospitalizations among the 65 and older age group in New Jersey | Decreased by 31.2% |
| Percentage of COVID-19 patients admitted in the last month who were vaccinated at University Hospitals Cleveland Medical Center, Ohio | 2% |
| Percentage of COVID-19 patients admitted so far this year who were fully vaccinated at Sanford Health | Less than 5% |
| Percentage of vaccinated Americans hospitalized with COVID-19 | 1 out of every 25,000 |
| Percentage of vaccinated COVID-19 patients hospitalized in the first half of 2021 with mild or asymptomatic infections | 57% |
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What You'll Learn

Less than 4% of hospitalized US kids were vaccinated
According to a CDC-led study, less than 4% of vaccine-eligible US children hospitalized for COVID-19 between 2022 and 2024 were up to date with their vaccinations. The study, published in Pediatrics, analyzed data from the COVID-19–Associated Hospitalization Surveillance Network (COVID-NET) on demographic factors, underlying illnesses, vaccination status, and clinical outcomes of children aged 6 months to 17 years admitted to over 275 hospitals in 12 states.
Among all participants, 25.2% were admitted to an ICU, with slightly higher rates (30.7%) among those aged 12 to 17 years. Additionally, almost one-third required mechanical ventilation or a high-flow nasal cannula (HFNC), with 6.5% and 6.8% receiving invasive and non-invasive mechanical ventilation, respectively. The study also found that 16.7% were given HFNC, while 0.4% required extracorporeal membrane oxygenation, and 0.6% died in the hospital.
The underlying illnesses with the highest percentage of up-to-date vaccinations among children included immunosuppressive conditions (9.5%), feeding tube dependence (6.7%), and neurologic conditions (5.2%). Overall, 4.5% of participants with asthma and 3.1% of those born prematurely were current with their vaccinations. Among children aged 6 to 23 months, severe disease was associated with underlying chronic lung disease (adjusted risk ratio [aRR] of 1.5) and cardiovascular disease (aRR of 1.4). For children aged 2 years and older, severity was linked to chronic lung disease (aRR of 1.9), diabetes (aRR of 1.5), and neurologic conditions (aRR of 1.4).
The researchers emphasized the importance of increasing COVID-19 vaccination rates in children, particularly those at high risk for severe disease, to reduce pediatric hospitalizations and adverse outcomes. They also highlighted the role of maternal COVID-19 vaccination during pregnancy in protecting young infants who are not yet eligible for vaccination.
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Alabama reported 32% of hospitalized patients were vaccinated
Alabama reported that 32% of hospitalized patients were vaccinated for COVID-19 amid a record surge in cases in January 2022. This figure was reported by Alabama Hospital Association President Dr. Don Williamson, who also stated that over 1,100 patients were in state hospitals with COVID-19 on the previous Monday. This number was significantly lower than the 3,000 people hospitalized during the peak of earlier COVID-19 surges.
Despite the high number of hospitalizations, Dr. Williamson emphasized that this wave was different, with a lower proportion of vaccinated individuals among hospitalized patients. However, he had no knowledge of the percentage of vaccinated patients who had received COVID-19 booster shots. The low vaccination rate in Alabama, with less than 48% of the population fully vaccinated, contributed to the state having one of the lowest vaccination rates in the country.
During this surge, Alabama set a record for daily COVID-19 cases, with the highly infectious Omicron variant spreading rapidly throughout the state. While Omicron appeared to cause less severe disease than previous variants, health officials warned that it should not be taken lightly. They emphasized that the sheer rate of infection was concerning and could still lead to a significant number of hospitalizations.
Alabama's State Health Officer, Scott Harris, highlighted the seriousness of the situation, stating that they were seeing the highest daily case numbers since the pandemic began. The 7-day positivity rate in Alabama remained high, with more than one-third of COVID-19 tests coming back positive. While hospitalizations were increasing, they were not skyrocketing at the same pace as the surge in cases. Health officials attributed this to the lower severity of the Omicron variant compared to previous strains.
In summary, Alabama's report of 32% vaccinated hospitalized patients occurred during a challenging period with record COVID-19 cases and a low statewide vaccination rate. While the Omicron variant appeared less severe, health officials stressed the need for concern and encouraged infection avoidance to prevent hospitalizations and severe outcomes.
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Vaccinated COVID patients over 65
Vaccination is critical to protecting the health of those aged 65 and above. In the United States, the CDC recommends that people aged 65 and older receive two doses of the current COVID-19 vaccine. This age group is particularly vulnerable to severe COVID-19 infections, with 74% of cases reported by the CDC occurring among the elderly.
However, there are challenges to ensuring this age group is vaccinated. One issue is the lack of access to online patient portal systems, which can facilitate vaccine scheduling. According to a poll, 45% of adults aged 65 to 80 and 42% of all adults aged 50 to 80 had not set up an account with their health provider's portal system. This disparity is more pronounced among lower-income older adults, with about 54% lacking a patient portal account compared to 35% of higher-income seniors.
To address this issue, some healthcare providers have started notifying patients over 65 through their portal accounts when it's their turn to arrange a vaccination appointment. They can even schedule the appointment directly through the portal, which is accessible via the web or a smartphone app. For those without portal accounts, mailed letters are sent, inviting them to schedule appointments by phone.
It is important to note that the risk of severe illness from COVID-19 decreases with vaccination. While breakthrough cases can occur, only one out of every 25,000 fully vaccinated Americans has been hospitalized with COVID-19. This highlights the effectiveness of the vaccines in preventing severe disease and protecting the health of those over 65.
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Vaccines reduce COVID-related hospitalizations
Vaccines have proven to be highly effective in reducing COVID-related hospitalizations, serious illnesses, and deaths. While breakthrough infections can still occur in vaccinated individuals, the chances of hospitalization are significantly lower for those who have received their shots.
Data from various sources, including the CDC, have shown that only a small percentage of vaccinated individuals are hospitalized with COVID-19. For example, in one study, it was found that only one out of every 25,000 fully vaccinated Americans was hospitalized with the virus. This is strong evidence that vaccines provide a robust defense against severe disease, even in the face of new variants.
During a record surge in Alabama, it was reported that approximately 32% of hospitalized patients had been vaccinated for COVID-19. While this may seem like a significant proportion, it is important to consider that less than 48% of Alabama's population was fully vaccinated at the time, indicating that the unvaccinated were disproportionately affected.
Furthermore, studies have shown that vaccinated individuals who are hospitalized are more likely to have underlying risk factors such as older age, immunocompromised status, or chronic illnesses. In the case of children, less than 4% of those hospitalized with COVID-19 were vaccinated, with the majority having underlying chronic conditions. Maternal vaccination during pregnancy can also provide protection for young infants who are not yet eligible for vaccination.
While the effectiveness of vaccines in preventing hospitalization may wane over time, especially for older and immunocompromised individuals, the probability of a fully vaccinated person experiencing a breakthrough infection resulting in hospitalization is still very low, estimated to be between 1 in 5,000 to 1 in 10,000. Overall, vaccines have been instrumental in reducing COVID-related hospitalizations and continue to play a crucial role in mitigating the impact of the virus.
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Unvaccinated make up most COVID hospitalizations
COVID-19 vaccines have proven to be highly effective in reducing hospitalizations, serious illnesses, and deaths. However, as the pandemic has progressed, the percentage of vaccinated individuals among hospitalized COVID-19 patients has also increased. This can be attributed to various factors, including the emergence of new variants, waning vaccine immunity, and the increased opportunity for breakthrough infections as more people get vaccinated.
During the early stages of the pandemic, it was rare for fully vaccinated individuals to be hospitalized with COVID-19. For example, in Provincetown, Massachusetts, only four out of 469 people hospitalized during a COVID-19 outbreak in early July 2021 were fully vaccinated. Similarly, data from the same time period showed that only one out of every 25,000 fully vaccinated Americans was hospitalized with a breakthrough infection.
However, as the virus evolved and new variants emerged, the effectiveness of vaccines in preventing hospitalizations slightly decreased. For instance, during the Omicron surge in Alabama in January 2022, approximately 32% of hospitalized patients had been vaccinated. This marked a significant increase compared to the peak of earlier surges, when the state had around 3,000 hospitalized patients, the majority of whom were unvaccinated.
Additionally, the probability of a fully vaccinated person experiencing a breakthrough infection has increased over time. Dr. Syed Hussain, an expert in the field, estimated this probability to be between 1 in 5,000 and 1 in 10,000. This probability is influenced by various factors, including the time since vaccination, the emergence of new variants, and individual risk factors such as age and underlying health conditions.
While vaccinated individuals are still less likely to be hospitalized compared to their unvaccinated counterparts, it is important to recognize that hospitalizations among the vaccinated population are no longer as rare as they once were. This highlights the importance of staying up to date with vaccinations, including booster shots, to maintain protection against severe disease and hospitalization.
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Frequently asked questions
32% of hospitalized patients in Alabama were fully vaccinated.
Only 1 out of every 25,000 fully vaccinated Americans were hospitalized with COVID-19.
57% of vaccinated COVID-19 patients hospitalized in the first half of 2021 had mild or asymptomatic infections.
Less than 4% of hospitalized children were vaccinated.











































