
Hospital-acquired infections (HAIs) are a significant cause for concern in the healthcare industry, with tens of thousands of lives lost each year in the United States alone. The COVID-19 pandemic has further exacerbated the challenge of managing HAIs, with a shift in resources towards addressing the pandemic and an increase in hospitalisations. Prior to the pandemic, it was estimated that one in every thirty-one healthcare patients in the US was affected by HAIs, resulting in over 600,000 hospitalisations and 70,000 deaths annually. The World Health Organization (WHO) estimates that globally, hundreds of millions are affected by HAIs each year, with a significant impact on low- and middle-income countries. The growing incidence of chronic diseases and an ageing population, particularly in North America, are expected to contribute to the increasing prevalence of HAIs.
| Characteristics | Values |
|---|---|
| Number of hospital-acquired infections per year | Tens of thousands of Americans, 687,000 in the US, and hundreds of millions globally |
| Number of deaths caused by hospital-acquired infections per year | 70,000 in the US, 27,000 caused by C. diff alone, and 1 in 10 infected patients globally |
| Number of hospital-acquired infections caused by C. diff per year | 290,000 |
| Number of hospital-acquired infections per 1,000 bed-days in a Danish hospital trust from 2010 to 2014 | Not provided |
| Number of hospital-acquired infections in Pennsylvania hospitals in one year | 2,000 |
| Number of hospital-acquired infections in the US in 2015 | 3% of hospitalized patients had one or more HAIs |
| Number of hospital-acquired infections in the US between 2019 and 2020 | 24% increase in central line-associated bloodstream infections (CLABSI) |
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What You'll Learn
- Hospital-acquired infections (HAIs) kill tens of thousands of Americans annually
- COVID-19 has impacted the disinfectant market and HAI prevention efforts
- In 2015, 3% of US hospital patients had one or more HAIs
- In 2015, 72,000 US hospital patients with HAIs died during their hospitalizations
- In 2022, the WHO estimated that hundreds of millions worldwide are affected by HAIs annually

Hospital-acquired infections (HAIs) kill tens of thousands of Americans annually
Hospital-acquired infections (HAIs) are a significant cause for concern in the healthcare industry, particularly in the United States, where they claim tens of thousands of lives each year. According to the Centers for Disease Control and Prevention (CDC), Clostridium difficile or C. diff, a bacterium that causes hospital-acquired infections, sickens about 290,000 hospital patients annually and kills at least 27,000 people. This is just one type of HAI, and the overall impact of HAIs in the US is substantial.
Prior to the COVID-19 pandemic, it was estimated that HAIs affected approximately one in every thirty-one US healthcare patients, resulting in over 600,000 hospitalizations and 70,000 deaths annually. The pandemic has likely exacerbated the issue, as resources traditionally dedicated to infection prevention and control have been diverted to manage COVID-19. The full extent of the impact of the pandemic on HAI rates is yet to be determined.
The high prevalence of HAIs in the US has prompted the implementation of various preventative measures. These include improved hand hygiene, surface cleaning, touchpoint disinfection, and appropriate antibiotic use. According to the World Health Organization (WHO) and CDC, basic cleaning and infection prevention and control strategies can effectively combat the spread of infections. However, many hospitals struggle to control infections, and HAIs are spreading beyond healthcare facilities to places like nursing homes and patients' homes.
The overuse of antibiotics in hospitals is a significant contributor to the development of antibiotic-resistant "superbugs." According to the CDC, at least 30% of antibiotic prescriptions in hospitals are unnecessary or inappropriate, increasing patients' infection risk. This has led to concerns about the effectiveness of hospitals' infection prevention methods and calls for improved strategies to protect patient safety.
The impact of HAIs extends beyond the loss of life, also incurring substantial financial costs. The economic burden of HAIs in the US healthcare system is significant, with an estimated additional cost of $5 billion annually due to infections contracted in hospitals. This highlights the urgency of addressing HAIs and implementing effective prevention and control measures to reduce their occurrence and mitigate their impact on patient health and healthcare costs.
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COVID-19 has impacted the disinfectant market and HAI prevention efforts
Hospital-acquired infections (HAIs) are a significant cause of patient harm and increased healthcare costs. The COVID-19 pandemic has impacted the disinfectant market and HAI prevention efforts in several ways.
Firstly, the pandemic has caused a surge in demand for disinfectant products, including wipes and sprays. In March 2020, sales of aerosol/spray disinfectants grew by over 340% compared to the previous year. The sale of multipurpose cleaners also spiked by more than 160% during the same period. This increased demand has been driven by the need to prevent the transmission of COVID-19 and other infectious diseases.
Secondly, the pandemic has disrupted supply chains and created fluctuations in the raw material costs for disinfectant manufacturers. This has presented challenges for the industry in meeting the soaring demand for disinfectant products.
Thirdly, the diversion of resources towards COVID-19 response efforts has impacted HAI prevention initiatives. A survey revealed that a significant portion of infection prevention professionals was dedicating most of their time to COVID-19 response. This diversion of resources may have compromised surveillance, data collection, and mitigation efforts for HAIs, potentially leading to an increase in infection rates.
Furthermore, the pandemic has led to changes in hospital practices, longer patient stays, and more frequent use of medical devices. These factors have likely contributed to an increased potential for device-associated infections. For instance, data from the CDC's National Healthcare Safety Network (NHSN) showed significantly higher incidences of central line-associated bloodstream infections (CLABSIs), catheter-associated urinary tract infections (CAUTIs), ventilator-associated events (VAEs), and methicillin-resistant Staphylococcus aureus (MRSA) bacteremia in 2021 compared to 2019.
The impact of COVID-19 on HAI prevention highlights the need for healthcare systems to develop innovative approaches to support and strengthen their infection prevention programs during public health emergencies.
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In 2015, 3% of US hospital patients had one or more HAIs
Hospital-acquired infections (HAIs) are a significant cause of patient harm and increased healthcare costs. In 2015, 3% of hospital patients in the US had one or more HAIs, according to the National and State Healthcare-Associated Infections Progress Report HAI Hospital Prevalence Survey. This equates to an estimated 687,000 HAIs in the US that year.
HAIs affect approximately one in every thirty-one US healthcare patients, resulting in more than six hundred thousand hospitalizations and seventy thousand deaths annually. The COVID-19 pandemic has impacted HAI rates, with concerns that HAIs may increase due to factors such as the diversion of traditional infection prevention resources and increased use of invasive medical devices.
The prevalence of HAIs varies depending on hospital characteristics. Hospitals with large patient populations, older patients, or those specializing in infectious diseases tend to have higher infection rates. The types of infections also differ by place of acquisition, with higher rates of polymicrobial intra-abdominal infections in hospitals compared to other settings.
The financial burden of HAIs is substantial, with the cost of inpatient mortality reduction ranging from $1,381 to $1,640 per patient. Additionally, the overall healthcare costs associated with HAIs in the US amount to an estimated $5 billion annually.
To address HAIs, various strategies are employed, including touchpoint disinfection services, improved hand hygiene compliance, limiting antibiotic use, and implementing multiple infection-control measures. The demand for disinfectants and infection control devices is expected to increase in the market, particularly in North America due to the growing incidence of chronic diseases and an aging population.
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In 2015, 72,000 US hospital patients with HAIs died during their hospitalizations
Hospital-acquired infections (HAIs) are a significant cause of patient harm and increased healthcare costs. Prior to the COVID-19 pandemic, HAIs were a serious issue in US healthcare facilities, affecting approximately one in every thirty-one patients and resulting in hundreds of thousands of hospitalizations and deaths annually.
In 2015, it was reported that 72,000 US hospital patients with HAIs died during their hospitalizations. This highlights the severity and impact of HAIs on patient outcomes and the healthcare system. The COVID-19 pandemic has further exacerbated the challenges associated with HAIs, with concerns about the increased risk of infections due to resource diversion, supply chain issues, the use of invasive medical devices, and the increased use of antibiotics.
The high rate of HAIs has prompted the implementation of various preventive measures and interventions. These include improved hand hygiene, touchpoint disinfection, routine surface cleaning, and the appropriate use of antibiotics. According to the World Health Organization (WHO), basic infection prevention and control strategies can effectively combat the spread of HAIs. Additionally, the demand for disinfectants and infection control devices is expected to increase in the healthcare market.
The impact of HAIs extends beyond patient harm and includes significant financial implications. The increased healthcare costs associated with treating HAIs result in a substantial economic burden on the healthcare system. Efforts to improve infection prevention and control are crucial in reducing the prevalence and impact of HAIs, ultimately improving patient safety and healthcare outcomes.
The growing incidence of chronic diseases, such as cancer and kidney disease, and an aging population also contribute to the increasing prevalence of HAIs. Geriatric patients are more susceptible to infections due to their compromised immune systems and longer hospital stays. As the demand for healthcare services increases, the importance of effective infection control protocols and improved healthcare expenditures becomes more critical in addressing the challenge of HAIs.
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In 2022, the WHO estimated that hundreds of millions worldwide are affected by HAIs annually
Hospital-acquired infections (HAIs) are a significant cause of concern within the healthcare industry. In 2022, the World Health Organization (WHO) estimated that hundreds of millions of people worldwide are affected by HAIs annually. This estimate highlights the global impact of HAIs, which are often preventable. The COVID-19 pandemic has further exacerbated the challenges associated with HAIs, as resources have been diverted from infection prevention to managing the outbreak.
Prior to the COVID-19 pandemic, HAIs already posed a serious issue for healthcare facilities in the United States, affecting approximately one in every thirty-one patients. This resulted in a significant number of hospitalizations and deaths, with more than six hundred thousand hospitalizations and seventy thousand deaths in a single year. The impact of the pandemic on HAI rates is still being determined, but it has likely been affected by factors such as the diversion of resources and personal protective equipment, supply chain issues, and the increased use of invasive medical devices and antibiotics.
The increasing prevalence of HAIs is not limited to the United States. Globally, the growing incidence of chronic diseases, an aging population, and rising hospital admissions are contributing to the rise in HAIs. North America, in particular, is expected to have the largest share of the global hospital-acquired infection control market due to these factors. The demand for infection control devices and protocols is expected to increase in the coming years, with a focus on sterilization, disinfectants, and personal protective equipment such as gloves, masks, and hand sanitizers.
The impact of HAIs extends beyond patient harm, as they also incur significant healthcare costs. In the United States, about 90,000 deaths per year are attributed to infections contracted inside hospitals, adding an estimated $5 billion to the nation's annual healthcare bill. Additionally, HAIs can spread beyond hospital settings, affecting doctor's offices, nursing homes, and even patients' homes. Clostridium difficile (C. diff) and methicillin-resistant Staphylococcus aureus (MRSA) are examples of HAIs that have spread beyond hospitals, with C. diff alone sickening about 290,000 hospital patients per year and killing at least 27,000.
To combat the spread of HAIs, basic infection prevention and control strategies are crucial. This includes routine surface cleaning, touchpoint disinfection, and high levels of hand hygiene compliance. Improved hand hygiene has been shown to reduce MRSA infections by 50% in the United States. Additionally, limiting the overuse of antibiotics is essential, as their inappropriate use can increase the risk of infection and contribute to the development of antibiotic-resistant "superbugs".
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Frequently asked questions
According to the World Health Organization (WHO), hundreds of millions of people are affected by hospital-acquired infections (HAIs) every year. In the US, around 1.7 million HAIs occur annually, and about 1 in 31 hospital patients has at least one HAI on any given day.
In the US, approximately 99,000 people die from HAIs each year. Globally, 1 in 10 patients affected by HAIs dies from the infection, resulting in about 9.5 million deaths per year in low-income countries.
The most common types of HAIs include bloodstream infections, surgical site infections, urinary tract infections, and various pneumonias.
Yes, many HAIs are preventable. Basic infection control measures, such as handwashing, clean water, waste management, and environmental cleaning, can significantly reduce the spread of infections in healthcare settings.
In the US, the economic burden of HAIs is significant, with estimated healthcare costs of $20 billion per year.





























