
Allergic reactions can range from mild to severe, with severe reactions requiring immediate hospitalisation. Anaphylaxis is a severe allergic reaction that requires urgent emergency first aid, including the use of an adrenaline auto-injector (such as an EpiPen) and a visit to the emergency room. Hospitals can administer epinephrine, which helps bring blood to vessels and opens up airways, and monitor patients for at least four hours to prevent biphasic anaphylaxis, where symptoms return after initial recovery. Hospitals can also provide allergy tests to determine the cause of the reaction and refer patients to allergy specialists.
| Characteristics | Values |
|---|---|
| First course of action | Administer epinephrine (EpiPen) if available |
| If EpiPen is not available | Go to ER right away |
| If EpiPen is administered | Still need to call 911 or go to the ER |
| If having trouble breathing | ER is the best bet |
| Minimum stay in the ER | 4 hours |
| Carry | Two epinephrine devices at all times if at risk |
| If experiencing an allergic reaction | Lie down and elevate the legs |
| If the allergic reaction is from a bee sting | Try scraping the stinger off with a credit card or fingernail |
| If at risk of a severe allergic reaction | Have an ASCIA Action Plan for Anaphylaxis |
| If at risk of a severe allergic reaction | Carry a mobile phone to call for help |
| If at risk of a severe allergic reaction | Wear medical identification jewellery |
| If at risk of a severe allergic reaction | Avoid medication that may increase the severity of an allergic reaction |
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What You'll Learn

Administering epinephrine
Recognition of Anaphylaxis
Anaphylaxis is a severe allergic reaction that can be life-threatening. It is essential to recognize the signs and symptoms of anaphylaxis, which can include difficulty breathing, a weak and rapid pulse, severe swelling, confusion, and loss of consciousness. Recognizing these symptoms is crucial in identifying the need for epinephrine administration.
Immediate Administration
Epinephrine should be administered immediately if a person is experiencing anaphylaxis. It is recommended to use an adrenaline auto-injector, such as an EpiPen, by pressing it into the person's outer mid-thigh. This fast-acting medication helps bring blood to the vessels and opens up the airways, alleviating breathing difficulties. The auto-injector is designed for ease of use, even by those without medical training.
Dosage and Biphasic Reactions
A single dose of epinephrine may not always be sufficient to control anaphylaxis. In some cases, symptoms may return after an initial improvement, known as a biphasic reaction. This can occur up to 12 hours after the initial symptoms. Therefore, it is crucial to seek emergency medical care after administering epinephrine, as additional doses may be required.
Emergency Medical Care
Following the administration of epinephrine, it is essential to call emergency services (911 in the US) and seek immediate medical attention. Anaphylaxis requires urgent medical care, including potential hospitalization, to monitor the patient and provide further treatment if needed. Hospitalization allows for continuous observation and the administration of additional medications to manage symptoms and prevent complications.
Patient Education and Prevention
For individuals at risk of anaphylaxis, it is crucial to carry two epinephrine auto-injectors at all times. Doctors will prescribe these injectors if a person is at risk, and they should be replaced before their expiration date. Additionally, individuals should be educated on how and when to use the auto-injectors, and a written step-by-step plan should be developed and shared with relevant caregivers.
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Visiting the emergency room
Allergic reactions can range from mild to severe. Mild allergic reactions may not require a visit to the emergency room, but severe allergic reactions can have serious, life-threatening consequences if not treated immediately. If you or someone else is experiencing an anaphylactic allergic reaction, administer epinephrine (via an EpiPen) if it is available. Epinephrine helps bring blood to your vessels and opens up your airways if you are having trouble breathing.
If an EpiPen is not available, go to an ER right away. You will still need to call emergency services or go to the ER after administering epinephrine because one injection may not be enough, and you may have a delayed reaction. If you're having trouble breathing, an ER is your best bet because urgent care doesn't have the capacity to intubate, which is when a tube is inserted through the mouth or nose and then down into the windpipe.
If you know what your allergy triggers are, it is important to avoid them as much as possible to prevent an allergic reaction. However, many patients who go to an ER don't know what their triggers are, so it can be difficult for doctors to pinpoint the cause of the reaction. If you do visit the ER for an allergic reaction, expect to stay there for at least four hours to make sure your symptoms are under control.
Upon arrival at the ER, your provider might ask you questions about previous allergic reactions and you might be given a blood test to measure the amount of a certain enzyme (tryptase) that can be elevated up to three hours after anaphylaxis. You might be tested for allergies with skin tests or blood tests to help determine your triggers. During an anaphylactic attack, you might receive cardiopulmonary resuscitation (CPR) if you stop breathing or your heart stops beating. You might also be given medications, including:
- Epinephrine (adrenaline) to reduce the body's allergic response
- Intravenous (IV) antihistamines and cortisone to reduce inflammation of the air passages and improve breathing
- A beta-agonist (such as albuterol) to relieve breathing symptoms
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Identifying triggers
An allergic reaction occurs when the body's immune system reacts to a certain substance, with symptoms ranging from mild to severe. Severe allergic reactions, also known as anaphylaxis, can be life-threatening and require immediate medical attention. To effectively identify triggers, several strategies and tests can be employed:
Patient History and Symptom Analysis
When a patient presents with an allergic reaction, healthcare professionals will typically start by taking a detailed patient history. This includes asking questions about the specific symptoms experienced, the timing of the reaction, and any potential allergens that the patient may have been exposed to. Understanding the chronology of symptoms can provide valuable insights into the trigger. For example, food allergies typically cause reactions within minutes to hours, while immune complex reactions may have a delayed onset.
Allergy Testing
Allergy testing plays a crucial role in identifying specific triggers. Skin tests, also known as scratch or prick tests, are commonly used. These involve placing a small amount of the suspected allergen on the skin, usually the forearm, and then pricking the skin to allow the allergen to penetrate. If a person is allergic to the substance, a localized reaction, such as redness or swelling, will occur at the test site.
Blood tests are another valuable tool for allergy testing. These tests measure the presence of specific antibodies, such as immunoglobulin E (IgE), which are produced by the body in response to particular allergens. By evaluating these antibody levels, healthcare providers can identify potential triggers.
Environmental Assessments
For individuals who experience allergic reactions without a known cause, conducting a thorough environmental assessment can be beneficial. This involves evaluating the patient's home, school, or workplace for potential allergens. Common environmental allergens include pollen, pet dander, dust mites, and mould. By identifying and addressing these allergens, patients can better manage their exposure and prevent future allergic reactions.
Food Diary and Elimination Diets
For individuals with suspected food allergies, keeping a detailed food diary can be immensely helpful. Recording meals, snacks, and any symptoms experienced can help identify potential food triggers. Additionally, under medical supervision, an elimination diet may be recommended, which involves removing specific foods or groups of foods from the diet and then gradually reintroducing them to pinpoint the culprit.
Patient Education and Awareness
Educating patients about common allergens and providing resources to help them identify triggers is essential. This includes raising awareness about various allergens, such as foods, medications, insect stings, and environmental factors. Encouraging patients to read product labels, inquire about ingredients in restaurants, and be vigilant about their surroundings can empower them to make informed choices and avoid potential triggers.
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Preventing anaphylaxis
Anaphylaxis is a severe and potentially life-threatening allergic reaction. It can occur within seconds or minutes of exposure to an allergen, and sometimes even hours later. The symptoms include difficulty breathing, a rapid weak pulse, skin rash, nausea and vomiting. It is imperative to seek immediate medical attention in the event of anaphylaxis.
Anaphylaxis is a severe allergic reaction that requires urgent medical attention. While there is currently no cure for allergies, anaphylaxis can be prevented by avoiding exposure to the allergen. Here are some steps to prevent anaphylaxis:
- Avoid allergens: The best way to prevent anaphylaxis is to avoid the allergen that triggers the reaction. This may include avoiding certain foods, medications, insect stings, or other allergens. It is important to read food labels carefully, ask about ingredients and preparation methods at restaurants, and inform caregivers, schools, and healthcare providers about your allergies.
- Adrenaline injectors: If you are at risk of anaphylaxis, your doctor will prescribe an adrenaline injector (EpiPen® or Anapen®). It is important to always carry your injector with you and know how to use it. Adrenaline works fast to reverse a severe allergic reaction, and these injectors are designed for use by people without medical training.
- Action plans: Work with your doctor or allergy specialist to develop an action plan for managing your allergies and preventing anaphylaxis. This may include an Australasian Society of Clinical Immunology and Allergy (ASCIA) Action Plan for Anaphylaxis, which provides guidelines for emergency management and education on injector use.
- Medical identification jewellery: Consider wearing medical identification jewellery, which can help ensure that adrenaline is administered promptly in an emergency.
- Avoid certain medications: Medications such as beta-blockers may increase the severity of an allergic reaction or complicate its treatment. Discuss with your healthcare provider to ensure you are prescribed safe alternatives.
- Allergy testing and education: If you are at risk of anaphylaxis, consult an allergy specialist for advice on prevention and management. They can provide accurate testing and advice on dietary and lifestyle restrictions to prevent allergic reactions.
It is important to note that even with precautions, accidental exposure to allergens can still occur. Always carry your adrenaline injector and follow your action plan if you experience anaphylaxis symptoms.
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Treating symptoms
An allergic reaction can range from mild to severe. Mild allergic reactions may not require hospital treatment, but severe allergic reactions can have serious, life-threatening consequences if not treated immediately.
If someone is experiencing a severe allergic reaction, it is important to administer epinephrine (adrenaline) immediately. Epinephrine helps bring blood to vessels and opens up airways if the person is having trouble breathing. It can be administered via an EpiPen or an Anapen, which are designed for use by people with no medical training. If an EpiPen is not available, it is important to get to an emergency room right away.
If someone is experiencing anaphylaxis, they should not stand or walk at any time, even if they feel better. They should lie down, preferably with their legs elevated, and be kept warm with a jacket or blanket. This can help prevent shock and keep the individual calm. If they are experiencing discomfort in this position, they should stay still before help arrives. If the person is having trouble breathing, an ER is the best option because urgent care does not have the capacity to intubate.
If the allergic reaction is due to a bee sting, try to remove the stinger by scraping it off with a credit card or fingernail. Do not use tweezers, as these can release more venom into the sting site.
If the person is unresponsive and not breathing normally, commence cardiopulmonary resuscitation (CPR). If the person has asthma, follow their asthma action plan and give them their asthma reliever puffer.
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Frequently asked questions
If you think you're having an allergic reaction, you should seek medical attention immediately. If you have an EpiPen, use it, and call 999 or ask someone else to. Lie down, and if you're struggling to breathe, raise your legs or sit up slowly.
If someone else is having an allergic reaction, you should use their EpiPen if they have one, and call 999. Lie them down, and if they're struggling to breathe, help them to sit up slowly. Check their pulse and breathing, and if necessary, perform CPR.
When you get to the hospital, you will be seen by a doctor who will assess your symptoms and may give you further medication. You will usually stay in the hospital for around 2 to 12 hours, but you may need to stay longer.
Before you leave the hospital, you will be given two EpiPens to keep in case you have another allergic reaction. You will also be advised to see an allergist for a full panel of tests to identify your triggers.











































