Logan Reid
The United States is home to some of the world's best hospitals for cancer treatment, with Newsweek ranking 175 leading cancer hospitals in the country in 2023. The University of Texas MD Anderson Cancer Center in Houston and Memorial Sloan Kettering Cancer Center in New York City were ranked as the top two cancer hospitals in the U.S. in 2025. Other top cancer hospitals in the U.S. include the Mayo Clinic in Rochester, Minnesota, the Dana-Farber Brigham Cancer Center in Boston, Massachusetts, and the City of Hope Comprehensive Cancer Center in Duarte, California. These hospitals are known for their cutting-edge research, innovative treatments, and specialized care for various types of cancer.
| Characteristics | Values |
|---|---|
| Leading Cancer Hospital in America | University of Texas MD Anderson Cancer Center, Houston, TX |
| Memorial Sloan Kettering Cancer Center, New York, NY | |
| Other Leading Cancer Hospitals in America | Mayo Clinic, Rochester, Minnesota |
| Dana-Farber Brigham Cancer Center, Boston, MA | |
| Stanford Health Care-Stanford Hospital, Palo Alto, CA | |
| City of Hope Comprehensive Cancer Center, Duarte, CA | |
| Massachusetts General Hospital, Boston, MA | |
| Mount Sinai Hospital, New York, NY | |
| Johns Hopkins Hospital, Baltimore, MD | |
| Hospitals of the University of Pennsylvania-Penn Presbyterian Medical Center, Philadelphia | |
| UCLA Health, Los Angeles | |
| The ranking factors include patient experience, staffing, patient outcomes, infection prevention, timely and effective care, cancer outcomes, breast cancer screening, patient satisfaction, vaccination rates of staff, and more. |
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What You'll Learn
University of Texas MD Anderson Cancer Center
The University of Texas MD Anderson Cancer Center, located in Houston, Texas, is the largest cancer center in the world. It is one of the original three NCI-designated comprehensive cancer centers in the United States. The center is both a degree-granting academic institution and a cancer treatment and research facility. It is part of the Texas Medical Center, the largest medical center and life sciences destination globally.
The University of Texas MD Anderson Cancer Center has consistently ranked as the world's top hospital in oncology care and research. It was ranked the number one cancer hospital in the US by US News and World Report in 2023 and has held the top position 20 times in the last 23 years. The center also ranks first in the number of National Cancer Institute grants and invested $1.2 billion in research in fiscal year 2023. Additionally, it has received Magnet Nursing recognition from the American Nurses Credentialing Center.
The center was established using surplus World War II Army barracks and initially operated for ten years from a converted residence with 46 beds leased in a Houston hospital. In 1954, it moved to its current location in the Texas Medical Center, allowing for significant expansion and the development of state-of-the-art facilities. Throughout the 1960s and 1970s, the center continued to expand its research capabilities and patient care services.
The University of Texas MD Anderson Cancer Center offers a range of cancer treatment services and specializes in various cancer types, including breast cancer, colorectal cancer, dermatology and skin cancer, endocrine cancer, genitourinary cancer, gynecologic cancer, head and neck cancer, neurologic cancer, and thoracic cancer. It also operates several other locations within the Greater Houston area, such as MD Anderson League City and MD Anderson Sugar Land, each with their own specialties.
The center is highly regarded for its groundbreaking research and innovative clinical care, providing new therapies years before they become standard in the community. It has been recognized for its focus on patient care and education, as well as its leadership in cancer prevention. The University of Texas MD Anderson Cancer Center is committed to advancing cancer treatment and improving patient outcomes through specialized education, training, and innovative research initiatives.
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Memorial Sloan Kettering Cancer Center
MSK currently employs over 1,200 physicians and treats patients with approximately 400 types of cancer annually. The centre has been at the forefront of cancer research and treatment since its formation in 1960. It was designated as one of only three Comprehensive Cancer Centres nationwide when the US federal government launched its War on Cancer in the early 1970s.
MSK has been recognised for its exceptional patient care, breakthrough research, and contributions to educating the next generation of cancer scientists worldwide. In 2024, MSK physician-scientists Dr Andrea Cercek and Dr Vinod Balachandran were named to the TIME100 Health list of the 100 most influential individuals in health. The centre has also been recognised for its contributions to prostate cancer screening, with Dr Andrew Vickers raising awareness about the best way to use the PSA test.
MSK has several facilities, including the Bendheim Integrative Medicine Center, a stand-alone outpatient facility that began in 1999, and the David H. Koch Center for Cancer Care, which opened in January 2020. MSK also partnered with Montefiore Health and Mount Sinai Health System to open the New York Proton Center in 2019, the first proton therapy centre in New York State.
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Dana-Farber Brigham Cancer Center
The centre has 13 specialised disease treatment centres dedicated to providing individualised care for each patient's type of cancer. Their approach to treatment and care is personalised, with a deep understanding of the patient's cancer and their life, goals, and unique needs. The centre offers access to the latest treatments and pioneering clinical trials, including emerging cellular therapies, immuno-oncology in preoperative settings, and adaptive radiation therapy. Dana-Farber Brigham Cancer Center also has the highest-volume CAR T-cell therapy centre in New England and is one of the largest nationally.
The centre's team of experts provides each patient with personalised, multidisciplinary cancer care. Their doctors, nurses, and care staff work as a single multidisciplinary team to give patients confidence and help speed their recovery. The centre's clinical innovations include emerging cellular therapies, immuno-oncology in preoperative settings, and adaptive radiation therapy.
The Dana-Farber Brigham Cancer Center's website shares patient stories, which may include descriptions of actual medical results. These stories provide a glimpse into the centre's approach to personalised care and the impact it has had on the lives of its patients.
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Mayo Clinic-Rochester
The Mayo Clinic-Rochester in Rochester, Minnesota, is a leading cancer hospital in the United States. It is nationally ranked in 13 adult specialties and 10 pediatric specialties. The clinic is recognised for its holistic approach to cancer care and expertise, consistently ranking it among the top hospitals for cancer treatment in the nation by U.S. News & World Report.
The Mayo Clinic Comprehensive Cancer Center is committed to driving research breakthroughs that will change the way cancer prevention, screening, and treatment are approached. The centre is a member of the National Comprehensive Cancer Network (NCCN), a not-for-profit alliance dedicated to improving cancer care quality and accessibility. Every day, over 400 physicians and scientists at the centre dedicate themselves to finding answers for the unmet medical needs of people with cancer. The centre has four NCI SPORE grants, which facilitate collaboration between basic and clinical researchers to develop new and diverse approaches to cancer prevention, early detection, diagnosis, and treatment.
The Mayo Clinic Comprehensive Cancer Center is the only National Cancer Institute-Designated Comprehensive Cancer Centre with three locations in Arizona, Florida, and Minnesota. The centre's Community Outreach and Engagement Office works with community members and researchers to ensure that its cancer care, research, and clinical trials serve the needs of the community. Every year, more than 130,000 people with cancer come to the Mayo Clinic from all walks of life and from around the world to receive precision diagnoses and treatments tailored to their exact needs and cancer types.
The Mayo Clinic's cancer research efforts are extensive, spanning the spectrum of cancer research, including basic cancer biology, improving diagnosis and treatment, and finding new ways to deliver targeted cancer treatment. The clinic also offers access to hundreds of clinical trials in all phases, providing participants with earlier access to new treatments. Through programmes such as Cancer Research Training and Education Coordination (CRTEC), the Mayo Clinic is committed to training the next generation of cancer care professionals and researchers to ensure cancer expertise reaches every person, everywhere.
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City of Hope Comprehensive Cancer Center
City of Hope has been designated a Comprehensive Cancer Centre by the National Cancer Institute, a branch of the National Institutes of Health. It is also a founding member of the National Comprehensive Cancer Network (NCCN), a non-profit alliance of 21 U.S. cancer centres that publish clinical practice guidelines for oncological treatment. The centre's institutional goals are the prevention, treatment, and cure of cancer and other life-threatening diseases, including diabetes and HIV/AIDS.
City of Hope's main campus in Duarte has several treatment facilities for inpatient and outpatient care, including the Helford Clinical Research Hospital, the Michael Amini Transfusion Medicine Center, the Geri and Richard Brawerman Center for Ambulatory Care, and the Women's Center. The centre's clinical and translational research areas include Developmental Cancer Therapeutics, Cancer Immunotherapeutics, and Hematologic Malignancies, with a focus on innovative, disease-fighting strategies.
City of Hope is also constructing a $200 million, six-story cancer hospital in Orange County, slated to open in 2025. The centre is accredited by the Joint Commission and houses the Beckman Research Institute, the City of Hope Medical Foundation, and the Irell & Manella Graduate School of Biological Sciences. The institute's primary focus is research in cancer, diabetes, and HIV/AIDS, and it has contributed to advancements in recombinant DNA technology, gene therapy, and monoclonal antibodies.
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Frequently asked questions
The University of Texas MD Anderson Cancer Center in Houston was ranked number one in Newsweek’s World’s Best Specialized Hospital 2025 list for oncology.
Some other leading cancer hospitals in America include Memorial Sloan Kettering Cancer Center in New York, Dana-Farber Brigham Cancer Center in Boston, Mayo Clinic in Rochester, and City of Hope Comprehensive Cancer Center in Duarte, California.
Rankings are based on a variety of factors, including patient experience, staffing, patient outcomes, infection prevention, timely and effective care, cancer outcomes, and patient satisfaction.
Rankings are determined through a combination of surveys, accreditation data, and patient-reported outcomes measures (PROMs). Tens of thousands of medical professionals from various countries are invited to give recommendations across different specialties.
