
When it comes to melanoma treatment, several hospitals stand out for their expertise and innovative approaches. Melanoma is a complex disease that requires specialized care, and many medical centres are committed to providing the best treatment options. The Memorial Sloan Kettering Cancer Center, the oldest and largest hospital specialising in oncology treatment, is renowned for its melanoma program. It offers patients access to clinical trials of new treatments and has unparalleled skill in melanoma surgery, immunotherapy, and targeted therapy. The University of Texas MD Anderson Cancer Center is also highly regarded, ranked as the number one hospital for oncology treatment in the USA. Other notable mentions include Massachusetts General Hospital, Mount Sinai Hospital, and Johns Hopkins Hospital, all nationally ranked in several adult and pediatric specialties. AIM at Melanoma Foundation provides a list of melanoma specialists and encourages patients to consult them for their unique expertise in diagnosis and treatment.
| Characteristics | Values |
|---|---|
| Best Hospitals for Melanoma Treatment | MD Anderson Cancer Center, Memorial Sloan Kettering Cancer Center, Dana-Farber Cancer Institute, Mayo Clinic-Rochester, Massachusetts General Hospital, Mount Sinai Hospital, UCSF Health-UCSF Medical Center, Johns Hopkins Hospital, Stanford Health Care-Stanford Hospital, City of Hope Comprehensive Cancer Center |
| MD Anderson Cancer Center Location | Houston, Texas |
| Memorial Sloan Kettering Cancer Center Location | New York |
| Dana-Farber Cancer Institute Location | Brigham and Women's Hospital, Yawkey Center for Cancer Care |
| MD Anderson Cancer Center Treatments | Wide excision of the primary tumor, lymphatic mapping and sentinel lymph node biopsy, lymph node dissection |
| Memorial Sloan Kettering Cancer Center Treatments | Surgery, immunotherapy, targeted therapy, radiation therapy, rehabilitation |
| Dana-Farber Cancer Institute Treatments | Surgery, chemotherapy, radiation therapy, oncolytic virus therapy, immunotherapy |
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What You'll Learn

Memorial Sloan Kettering Cancer Center, New York
Memorial Sloan Kettering Cancer Center in New York is one of the best hospitals for melanoma treatment. It is the oldest and largest hospital in the world that specializes in oncology treatment. The hospital has a strong team of leading specialists from all areas of melanoma care, including surgery, immunotherapy, targeted therapy, radiation therapy, and rehabilitation.
The Memorial Sloan Kettering Cancer Center offers unparalleled skill and experience in melanoma surgery. The hospital's multidisciplinary team has particular expertise in treating large facial melanomas and melanomas that are challenging due to their size or location. They also have extensive experience in managing rare melanoma subtypes, such as lentigo maligna melanoma and acral lentiginous melanoma, as well as eye melanoma and mucosal melanoma.
The hospital provides access to clinical trials of new melanoma treatments that are not available elsewhere. These include new drug treatments and combinations of treatments, such as immunotherapy and targeted therapy, which have been pioneered at Memorial Sloan Kettering. The hospital's melanoma team has been at the forefront of developing and testing effective treatments over the past decade, significantly improving the outlook and quality of life for people with metastatic melanoma worldwide.
Memorial Sloan Kettering's doctors employ highly specialized approaches to treat in-transit melanoma, which has spread throughout a single leg or arm. They also offer 3-D total-body photography for melanoma screening, making them one of the only institutions globally to provide this technology. The hospital is committed to providing the best possible outcome for each patient by working together to choose the optimal combination of therapies.
The Memorial Sloan Kettering Cancer Center in New York has a rich history, as evidenced by its 64-year experience in treating patients with anorectal melanoma, as detailed in a publication from 1993. The center continues to be a leader in melanoma research and treatment, offering hope and advanced care to patients from all over the world.
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Herbert Irving Comprehensive Cancer Center, New York
The Herbert Irving Comprehensive Cancer Center (HICCC) is a National Cancer Institute (NCI)-designated cancer center located at the NewYork-Presbyterian/Columbia University Irving Medical Center. The center was founded in 1911 as the Institute for Cancer Research and has been a part of Columbia University since a merger in 1998. HICCC is currently led by Anil K Rustgi, MD, with Gary Schwartz serving as the deputy director.
HICCC has over 250 faculty members and 12 core facilities, with eight research programs divided into three divisions: basic research, disease-specific, and population science. The basic research division includes programs in cancer regulatory networks, cancer genetics, and epigenetics. The disease-specific division focuses on breast cancer, hematological cancer, prostate cancer, and neuro-oncology. The population science division includes cancer epidemiology, prevention, control, and disparities. The center receives substantial funding, with over $33 million from the National Institutes of Health alone.
The center's mission is to advance the understanding of cancer biology to develop effective cancer therapies and prevention strategies. HICCC's collaborative group of researchers and clinicians work together to provide optimal approaches for cancer prevention, diagnosis, and treatment. Their research and clinical programs have been significantly enhanced by a $700 million gift from Herbert and Florence Irving in 2017.
While specific details on melanoma treatment at HICCC are not readily available, as a comprehensive cancer center, they are likely to offer a range of treatment options for various cancers, including melanoma. The center's focus on research and collaboration suggests that patients can access innovative treatments and clinical trials, benefiting from the center's dedication to advancing cancer care.
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Kimberly and Eric J. Waldman Melanoma and Skin Cancer Center, New York
The Kimberly and Eric J. Waldman Melanoma and Skin Cancer Center at Mount Sinai in New York is a leading facility in the fight against melanoma and skin cancer. The centre was established in 2020 with a generous $10 million gift from the Waldman family.
The centre is named after the Waldman family and is housed within the Kimberly and Eric J. Waldman Department of Dermatology at the May Center for Mount Sinai Doctors, on 5 E. 98th Street in Manhattan. The Waldman Melanoma and Skin Cancer Center provides patients with comprehensive, coordinated services across the Mount Sinai Health System, in partnership with the Tisch Cancer Institute.
The centre brings together experts in oncology, dermatology, surgery, and pathology to provide patients with the latest scientific and therapeutic advances. The centre's leadership team includes Dr Emma Guttman-Yassky, a Waldman Professor and Chairwoman, as well as a team of reputable experts including dermatologists, surgeons, fellows, nurses and clinicians. All patients are assigned a patient navigator to help assist with scheduling appointments, receiving medications and specific treatments, and administrative support.
The Waldman Melanoma and Skin Cancer Center is equipped with state-of-the-art early detection technologies, including total body photography, reflectance confocal microscopy (RCM), optical coherence tomography (OCT), and electrical impedance spectroscopy (EIS). These technologies enable dermatologists to closely monitor and image lesions and perform non-invasive "blade-free biopsies". The centre also offers innovative technologies that collect skin cells through adhesive patches, avoiding the need for a scalpel, and 3D whole-body imaging systems that capture the entire skin surface to detect early skin cancer lesions.
The centre is committed to producing groundbreaking work in new skin cancer treatments and advancing early detection, treatment, and research. With the support of the Waldman family, the centre is well-positioned to become a leader in the field of melanoma and skin cancer research and treatment.
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University of Texas MD Anderson Cancer Center, Houston
The University of Texas MD Anderson Cancer Center in Houston, Texas, is a top-ranked hospital for melanoma treatment. It is the largest cancer center in the world and is consistently ranked #1 for cancer care and research in the US and worldwide. MD Anderson has held the #1 position 20 times in the last 23 years in the U.S. News & World Report's Best Hospitals rankings for cancer care. The hospital is managed as a non-profit and is part of the University of Texas System.
MD Anderson offers innovative melanoma treatment options, including surgery, lymphatic mapping, and sentinel lymph node biopsy. The type of melanoma surgery performed depends on the thickness of the melanoma tumour and whether it has spread. The most commonly performed procedure is a wide excision of the primary tumour, where the melanoma and a predetermined area around it are carefully cut out. The amount of skin removed and the degree of scarring depend on the tumour's thickness. Most patients do not need additional treatment after the excision.
In addition to surgery, MD Anderson also offers lymphatic mapping and sentinel lymph node biopsy, a minimally invasive surgical procedure. This procedure involves removing the regional lymph node(s) that receive lymph drainage from the primary tumour site to check for cancer spread. If the sentinel lymph node is cancer-free, no further treatment is needed. However, if it contains melanoma spread, further surgery or other treatments may be recommended.
MD Anderson also has a location in Madrid, Spain, which serves as its first global branch and is a Center of Excellence for cancer treatment in Spain and Europe. The hospital also has sister institution relationships with over 25 organisations worldwide, including the Tata Memorial Hospital in Mumbai, India, with which it collaborates on cancer research, education, and clinical care.
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Massachusetts General Hospital, Boston
The Massachusetts General Hospital in Boston is home to the nation's longest-standing Melanoma and Pigmented Lesion Center (PLC). The PLC has been at the forefront of cutaneous melanoma research and patient care for over 40 years, making it one of the major centres for melanoma patient care in New England.
The PLC takes a multidisciplinary approach to treating melanoma, handling all aspects of care required by early-stage patients. During an initial consultation, a team comprising a dermatologist, a cancer surgeon, and a melanoma pathologist examines the patient's moles and skin lesions. The team then works together to diagnose the precise condition and map out the most effective treatment.
The hospital has a high-risk unit that focuses on the initial surgical treatment and the first five years of post-melanoma surveillance. It also has a lower-risk "step-down" unit that continues surveillance for up to 10 years. Patients at extreme risk of melanoma due to genetic factors may remain under the hospital's care beyond this period.
The Massachusetts General Hospital has the only proton therapy site in New England, with two proton therapy centres. Leading specialists in the Department of Radiation Oncology use advanced radiation therapy techniques, such as conformal radiation therapy, to treat melanoma and other malignant skin tumours.
The hospital also places a special emphasis on genetic counselling, with over 200 melanoma-prone families from across the globe participating in its research efforts. This research aims to understand the fundamental causes of melanoma and the role of heredity and genetic factors in melanoma risk and therapy sensitivity.
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Frequently asked questions
Melanoma is a type of skin cancer.
Here is a list of some of the best hospitals for melanoma treatment in the US:
- Memorial Sloan Kettering Cancer Center in New York, NY.
- University of Texas MD Anderson Cancer Center in Houston, TX.
- Massachusetts General Hospital in Boston, MA.
- Mount Sinai Hospital in New York, NY.
- UCSF Health-UCSF Medical Center in San Francisco, CA.
- Johns Hopkins Hospital in Baltimore, MD.
- University Medical Center in Princeton, New Jersey.
Scores factor in patient safety, nurse staffing, patient experience, patient outcomes, and more.
It is important to find a cancer center with expertise and experience in melanoma treatment. Consider hospitals with specialists who are leaders in melanoma diagnosis, care, and treatment. Additionally, look for hospitals that offer personalized treatment plans and have access to cutting-edge technology and research.











































