
There are several hospitals around the world that are renowned for their pediatric cancer treatment and research. The U.S. News & World Report ranks St. Jude Children's Research Hospital as one of the best hospitals for cancer research and treatment, with top survival rates for aggressive childhood cancers like leukemia. The hospital has been pivotal in increasing the overall childhood cancer survival rate from 20% to over 80% in the US. Cincinnati Children's Hospital has also been consistently ranked highly, retaining the top spot for the second year in a row in the 2024-25 rankings. Dana-Farber/Boston Children's Cancer and Blood Disorders Center is another leading hospital, ranked as the second-best pediatric cancer program in the nation. Other notable hospitals include Children's Hospital of Philadelphia, Texas Children's Hospital, Children's National Hospital, and Children's Hospital Los Angeles, all nationally ranked in 11 pediatric specialties.
| Characteristics | Values |
|---|---|
| Ranking | St. Jude Children's Research Hospital, Cincinnati Children's, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Children's Hospital Los Angeles, Children's Hospital Colorado, Nationwide Children's Hospital, and Children's Hospital of Philadelphia are some of the top-ranked pediatric cancer hospitals in the US. |
| Survival Rates | Survival rates are an important factor in determining the best pediatric cancer hospitals. St. Jude Children's Research Hospital has significantly increased survival rates for childhood cancers, including acute lymphoblastic leukemia. |
| Accreditation | Accreditation and recognition are important indicators of quality. St. Jude Children's Research Hospital is recognized by the Magnet Recognition Program, which acknowledges excellence in nursing practice, leadership, and commitment to enhancing patient care. |
| Clinical Trials | Clinical trials are essential for improving pediatric cancer treatments. The Children's Hospital of Philadelphia, for example, offers access to top pediatric oncologists and multidisciplinary specialists conducting translational and clinical research initiatives to improve cure rates and reduce side effects. |
| Patient Safety | Patient safety is a critical aspect of hospital rankings. Institutions like St. Jude Children's Research Hospital prioritize patient safety by participating in networks like Children's Hospitals Solutions for Patient Safety to ensure continuous improvement. |
| Staffing | Adequate nurse staffing is another factor considered in hospital rankings. |
| Behavioral Health | The inclusion of a behavioral health category in the pediatric hospital rankings reflects a growing recognition of the mental health crisis among children. |
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What You'll Learn

St. Jude Children's Research Hospital in Memphis, TN
St. Jude Children's Research Hospital in Memphis, Tennessee, is a leading hospital in the fight against childhood cancer and other life-threatening diseases. Founded in 1962 by entertainer Danny Thomas, the hospital is built on the belief that "no child should die in the dawn of life". St. Jude's is a non-profit medical corporation that has pioneered treatments, helping to increase the overall childhood cancer survival rate from 20% to over 80% in the United States.
The hospital has achieved remarkable success in treating some of the most aggressive childhood cancers, including leukemia and medulloblastoma. Since its opening, the survival rate for acute lymphoblastic leukemia has skyrocketed from 4% to 94%. St. Jude's shares its breakthroughs with other medical professionals worldwide through initiatives like St. Jude Cloud and St. Jude Cure4Kids, contributing to improved care and treatment for children globally.
The hospital's Brain Tumor Treatment Program specializes in treating challenging pediatric brain tumors, and they are also committed to enhancing patient care and cultural sensitivity. St. Jude's collaborates with other institutions to ensure patient safety, as part of the Children's Hospitals Solutions for Patient Safety network. They also work with Le Bonheur Children's Medical Center in Memphis, where St. Jude patients can undergo procedures like brain surgery.
St. Jude Children's Research Hospital treats patients up to the age of 21 and, in some cases, up to 25. Notably, families never receive bills for treatment, as the hospital covers all costs. The daily operating costs average $1.7 million, funded by donations, fundraisers, and support from dynamic teams. St. Jude's is committed to finding cures and saving children's lives worldwide.
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Cincinnati Children's in Cincinnati, OH
Cincinnati Children's cancer experts specialize in providing personalized care to each patient and their family. They offer some of the most innovative treatments in the world, including next-generation sequencing to understand the genetic wiring of cancers and leukemias unresponsive to traditional therapies. The hospital is also a pioneer in developing precision therapies for young adults with pediatric cancers, considering their unique physiological and psychological needs.
The hospital's Young Adult Cancer Center is internationally acclaimed for its expertise in treating young adults with pediatric cancers. Their specialists have extensive experience in managing young adult cancer patients, offering them clarity and insight into their diagnoses and treatment options. The center also provides long-term follow-up and support through its Cancer Survivorship Center, ensuring cancer survivors receive the necessary education, resources, and specialized medical care to maintain a healthy lifestyle.
Cincinnati Children's is further distinguished by its Proton Therapy Center, delivering advanced proton therapy to destroy cancer cells while minimizing damage to healthy tissues and reducing side effects. Their Bone Marrow Transplant Program is another notable feature, with over 2,300 pediatric marrow and stem cell transplants performed, setting standards of care in numerous cancer centers across North America. The hospital's commitment to research and innovation, coupled with its comprehensive patient-centric approach, solidifies its reputation as one of the best pediatric cancer hospitals.
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Dana-Farber/Boston Children's Cancer and Blood Disorders Center
The center provides a wide range of treatment options, from standard protocols and advanced therapies to clinical trials. It also offers a comprehensive range of pediatric subspecialty resources, including neurologists, orthopedists, diagnostic imaging specialists, and pathologists, ensuring truly holistic care. The hospital is known for its expertise in treating various cancers and blood disorders, with several specialized centers.
The Brain Tumor Center at Dana-Farber/Boston Children's is world-renowned for its treatment of malignant and non-malignant brain and spinal cord tumors in children. The Hematologic Malignancy Center is recognized as one of the top pediatric leukemia and lymphoma treatment centers globally, pioneering treatments that have significantly increased survival rates. The Liver Tumor Center addresses all types of liver tumors, while the Solid Tumor Center treats cancers in bones, tissues, and organs.
The hospital is also a leader in pediatric stem cell research and transplants, with its Hematopoietic (Stem) Cell Transplant Program being one of the largest and most experienced in the world. Additionally, Dana-Farber/Boston Children's is a founding member of the Transatlantic Gene Therapy Consortium, utilizing gene therapy to treat childhood illnesses through international collaboration. Their clinical trials are unique and unavailable at other hospitals in New England.
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Children's Hospital Los Angeles
CHLA delivers the highest level of care to children, adolescents, and young adults with cancer and blood diseases. Their teams of experts work together to detect cancers earlier and deliver leading therapies, carefully considering each child's unique needs. CHLA offers innovative treatments and advanced medical training through fellowships in transplantation, hematology-oncology, neuro-oncology, and more. The hospital's Cancer and Blood Disease Institute welcomes new patients, referrals, and second opinions.
CHLA's Behavioral Health Institute is dedicated to training researchers and clinicians in the field of behavioral health care for children and adolescents. The hospital also offers a MyChildren'sLA portal to help patients stay connected with their care team.
CHLA is one of the best pediatric cancer hospitals in the United States, alongside St. Jude Children's Research Hospital, which has achieved high survival rates for some of the most aggressive childhood cancers, including leukemia and medulloblastoma. St. Jude has also pioneered cancer treatments that have helped increase the overall childhood cancer survival rate from 20% to more than 80% in the United States. Cincinnati Children's in Cincinnati, OH, and Dana-Farber/Boston Children's Cancer and Blood Disorders Center in Boston, MA, are also top-ranked pediatric cancer hospitals.
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Children's Hospital of Philadelphia
The Children's Hospital of Philadelphia is one of the best pediatric cancer hospitals in the United States. It has a steadfast commitment to providing exceptional patient care, training new generations of pediatric healthcare providers, and pioneering major research initiatives. The hospital's Cancer Center offers comprehensive, family-centred care with over 40 pediatric oncologists, with expertise in every type of childhood cancer, from the rarest to the most common. The hospital also has the largest pediatric oncology research program in the United States, quickly translating scientific discoveries into clinical therapies.
The Children's Hospital of Philadelphia provides cutting-edge treatments and services that are not available anywhere else. For instance, it is one of the few pediatric cancer programs with a dedicated team for caring for children with solid tumors. The hospital also has an experienced proton therapy team that has treated over 800 patients and is equipped to care for children transitioning their cancer care from other hospitals. Additionally, the hospital offers specialized rehabilitative care at the Children's Seashore House Center for Rehabilitation, providing both inpatient and outpatient therapies.
The Center for Childhood Cancer Research at the hospital brings together investigators from multiple disciplines with the goal of eradicating childhood cancer. They pursue this goal through basic, clinical, and translational research, aiming to bring advancements from the lab to the bedside. The hospital also has a Solid Tumor Program and a Neuro-Oncology Program, which is one of the largest pediatric programs dedicated to treating children with brain and spinal cord tumors.
The Children's Hospital of Philadelphia is ranked among the top pediatric cancer centres in the nation by U.S. News & World Report and Newsweek. Its rankings reflect the hospital's commitment to excellence in patient care, research, and training. The hospital's pediatric cancer team guides patients and their families through the treatment journey, offering medical care, emotional counselling, and support for family members.
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Frequently asked questions
There is no definitive answer to this question as it depends on various factors and can vary from year to year. However, according to US News & World Report, the top pediatric cancer centers in the 2024-25 rankings were Cincinnati Children's and Dana-Farber/Boston Children's Cancer and Blood Disorders Center.
Other hospitals that are consistently ranked highly include St. Jude Children's Research Hospital, Children's Hospital Los Angeles, Children's Hospital of Philadelphia, Texas Children's Hospital, Children's National Hospital, Children's Hospital Colorado, Nationwide Children's Hospital, and Seattle Children's Hospital.
The rankings are based on various factors, including survival rates for different types of cancer, bone marrow transplant services, programs for brain tumors, infection prevention, accreditation, clinical data, safety, nursing staff, and patient questionnaires.
Clinical trials are a way to access state-of-the-art cancer care and potentially benefit from newer treatments. They are also a way for doctors to learn better methods to treat cancer. You can find clinical trials by talking to your child's cancer care team, who can advise you on the potential benefits and drawbacks of enrolling your child in a trial.
You can refer to the rankings provided by organizations such as US News & World Report or look for hospitals that are designated as Magnet hospitals, which have been recognized for their quality nursing care and patient outcomes. Additionally, consider the specific needs of your child and the specialties offered by the hospital.




































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